843. The PALM Consortium: A Multicenter, Multioutbreak Randomized Controlled Trial of Ebola Virus Disease Therapeutics
نویسندگان
چکیده
منابع مشابه
Clinical Evaluation of Ebola Virus Disease Therapeutics.
Ebola virus disease (EVD) was first described over 40 years ago, but no treatment has been approved for humans. The 2013-2016 EVD outbreak in West Africa has expedited the clinical evaluation of several candidate therapeutics that act through different mechanisms, but with mixed results. Nevertheless, these studies are important because the accumulation of clinical data and valuable experience ...
متن کاملEffects of Citrulline on Non-alcoholic Fatty Liver Disease: A Randomized-controlled Clinical Trial
Background and Objectives: Citrulline (cit.) is a non-essential amino acid derived from watermelon, which affects improving glucose tolerance and lipid and energy metabolisms. The aim of this study was to investigate effects of citrulline supplementation on non-alcoholic fatty liver. Materials & Methods: In this randomized clinical trial, 50 patients with NAFLD were randomly assigned to recei...
متن کاملDexamethasone vs Hydrocortisone in Management of Exacerbated Chronic Obstructive Pulmonary Disease Patients: A Randomized Controlled Trial
Background: Different types of corticosteroids with different characteristics, such as hydrocortisone and dexamethasone, have been used in treatment of exacerbated chronic obstructive pulmonary disease but drug of choice unclear. The main goal of present study was to compare the efficacy of hydrocortisone and dexamethasone on clinical symptoms, peak expiratory flow, oxidative stress factors and...
متن کاملAnemia during Hospitalization in the Patients with Ebola Virus Disease
Ebola virus disease is the important emerging disease in Africa. This infection is deadly and has the main clinical feature as an acute hemorrhagic fever. The main hematological alteration in this infection is the platelet change. However, the change in other hematological parameters should be mentioned.
متن کاملA multicenter, randomized, controlled trial of dexamethasone for bronchiolitis.
BACKGROUND Bronchiolitis, the most common infection of the lower respiratory tract in infants, is a leading cause of hospitalization in childhood. Corticosteroids are commonly used to treat bronchiolitis, but evidence of their effectiveness is limited. METHODS We conducted a double-blind, randomized trial comparing a single dose of oral dexamethasone (1 mg per kilogram of body weight) with pl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2019
ISSN: 2328-8957
DOI: 10.1093/ofid/ofz359.028